Pharmaceutical Refrigeration in Ireland

Pharmaceutical products such as vaccines, diagnostic kits, blood samples, medicines, need to be stored at predefined temperature and humidity levels in order to be compliant with FDA and other regulations. Therefore strict temperature and humidity control of these high value inventories is essential. These rules apply to all industrial pharmaceutical refrigeration in Ireland and the UK.

There has been a surge of the use of drugs that need pharmaceutical refrigeration, in Ireland and the UK. But what is the science behind why pharmaceutical products should be kept in cold storage?

Using a vaccine as an example, the vaccine must be kept cold for a variety of reasons. Depending on the vaccine, keeping it cold preserves pharmaceutical refrigeration irelandthe activity of the vaccine and slows the rate at which particles vibrate. Many vaccines consist mainly of protein (eg the hepatitis B vaccine). These proteins need to have the correct shapes if they are to induce immunity. Keeping the proteins cold helps to preserve the shape or the proteins will ‘denature’ and will not be fit for purpose.

Other vaccines consist of live microorganisms (eg the chickenpox vaccine). These vaccines need to be kept cold because the viruses aren't that stable outside of the cells they infect, and keeping them cold preserves their infectivity.

It is this biological background that makes pharmaceutical refrigeration in Ireland and the UK necessary as drug providers have a responsibility in keeping millions of people in good health via the products they provide. Therefore, regulation must be kept tight throughout the whole of the pharmaceutical cold chain to ensure products are of the highest quality.

CRS provide cold storage and pharmaceutical refrigeration in Ireland and the UK. With a wide range of cold storage products and services available CRS is well equipped to handle the cold storage needs for a range of industries such as food and drink, meat, catering and retail industries. For more information, please visit www.crs.ie.  

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